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ea0099ep80 | Thyroid | ECE2024

A severe case of ophthalmopathy in a primary hypothyroid patient

Vladica Diana , Dumitru Nicoleta , Alexandrescu Daniela , Mariana Ghemigian Adina

Introduction: Thyroid-associated ophthalmopathy (TAO) represents a common extrathyroidal manifestation of GravesÂ’ disease, however 2-7.5% of primary hypothyroid patients can experience a form of TAO as well. This condition is a rare autoimmune disease, where auto-antibodies (anti-TSH receptor antibodies or TRAb) target antigens shared by the thyroid and the orbit. This results in the inflammation, swelling and bulging of the eyes and surrounding orbital tissues. There are...